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Aplevant 1.5mg Pre-filled Pen (0.5ml Each)

℞
Prescription Required
Store in a refrigerator (2 - 8C). Do not freeze.
MRP₹5,669.0020% OFF
₹4,535.20

Inclusive of all taxes

Packaging:2.0 Solution for Injection in 1 box
Aplevant 1.5mg Pre-filled Pen (0.5ml Each) – Dulaglutide (1.5mg) 1.5 mg by Lupin Ltd — photo 1 of 3
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Quick Facts

Chemical ClassGlucagon-like Peptide-1 (GLP-1) Analogue
Habit FormingNo
Therapeutic ClassANTI DIABETIC
Action ClassInsulin Secretogogues: GLP-1 agonists

About Aplevant 1.5mg Pre-filled Pen (0.5ml Each)

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is an injectable medicine used to lower blood glucose levels in adults with type 2 diabetes. It works by helping your body produce insulin and reducing the amount of sugar your liver makes.The dose of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) will depend on your condition and what other diabetes medicines you are taking. You can use it at any time of day with or without food but try to use it on the same day each week to get the most benefit. Your doctor or nurse will show you how and where to inject the medicine. Follow the instructions carefully. Do not stop taking this medicine without talking to your doctor. If you do, your blood glucose levels may increase and put you at risk of serious complications. It should be used with a proper diet and exercise to control high blood glucose. Aplevant 1.5mg Pre-filled Pen (0.5ml Each) should be stored in a fridge until you need it but do not freeze it.The most common side effects of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) include nausea, diarrhea, abdominal pain, and loss of appetite. It can also lead to hypoglycemia (low blood sugar level) especially if you are taking other medicines to lower blood sugar. Make sure you know how to recognize and deal with it.Before using this medicine, talk to your doctor if you have ever had liver or kidney disease, pancreatitis, or stomach problems. Also, tell your doctor if you are taking any other medicines which may affect the way this medicine works. If you are pregnant or breastfeeding, ask your doctor if it is safe to take Aplevant 1.5mg Pre-filled Pen (0.5ml Each).

How It Works

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is an injectable medicine used to lower blood glucose levels in adults with type 2 diabetes. It works by helping your body produce insulin and reducing the amount of sugar your liver makes.The dose of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) will depend on your condition and what other diabetes medicines you are taking. You can use it at any time of day with or without food but try to use it on the same day each week to get the most benefit. Your doctor or nurse will show you how and where to inject the medicine. Follow the instructions carefully. Do not stop taking this medicine without talking to your doctor. If you do, your blood glucose levels may increase and put you at risk of serious complications. It should be used with a proper diet and exercise to control high blood glucose. Aplevant 1.5mg Pre-filled Pen (0.5ml Each) should be stored in a fridge until you need it but do not freeze it.The most common side effects of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) include nausea, diarrhea, abdominal pain, and loss of appetite. It can also lead to hypoglycemia (low blood sugar level) especially if you are taking other medicines to lower blood sugar. Make sure you know how to recognize and deal with it.Before using this medicine, talk to your doctor if you have ever had liver or kidney disease, pancreatitis, or stomach problems. Also, tell your doctor if you are taking any other medicines which may affect the way this medicine works. If you are pregnant or breastfeeding, ask your doctor if it is safe to take Aplevant 1.5mg Pre-filled Pen (0.5ml Each).

How to Use

Your doctor or nurse will guide you how to use this medicine.

What if you miss a dose?

If you miss a dose of Aplevant 1.5mg Pre-filled Pen (0.5ml Each), take it as soon as you remember. If the next dose is to be taken within the next 72 hours, skip the missed dose. Do not take 2 doses of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) within 72 hours of each other.

Storage

Store in a refrigerator (2 - 8C). Do not freeze.

Prescription required. Upload a valid prescription at checkout or via prescription upload.

Composition of Aplevant 1.5mg Pre-filled Pen (0.5ml Each)

Uses of Aplevant 1.5mg Pre-filled Pen (0.5ml Each)

Treatment of Type 2 diabetes mellitus

Key Benefits of Aplevant 1.5mg Pre-filled Pen (0.5ml Each)

  • In Treatment of Type 2 diabetes mellitus Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is an injectable medicine that helps to control high blood glucose (sugar) levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control the level you will reduce the risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs. Proper control of diabetes may also lessen your risk of having a heart attack or stroke. Taking Aplevant 1.5mg Pre-filled Pen (0.5ml Each) regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed as it is protecting your future health.

Side Effects of Aplevant 1.5mg Pre-filled Pen (0.5ml Each)

  • Nausea
  • Diarrhea
  • Vomiting
  • Abdominal pain
  • Loss of appetite

This is not a complete list of side effects. Consult your doctor if you experience any unusual symptoms.

Safety Advice for Aplevant 1.5mg Pre-filled Pen (0.5ml Each)

Alcohol
UNSAFE

It is unsafe to consume alcohol with Aplevant 1.5mg Pre-filled Pen (0.5ml Each).

Pregnancy
CONSULT YOUR DOCTOR

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast Feeding
CONSULT YOUR DOCTOR

Information regarding the use of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) during breastfeeding is not available. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR

It is not known whether Aplevant 1.5mg Pre-filled Pen (0.5ml Each) alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney
SAFE IF PRESCRIBED

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is safe to use in patients with kidney disease. No dose adjustment of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is recommended.However, monitor renal function in patients with renal impairment reporting severe adverse gastrointestinal reactions. Use Aplevant 1.5mg Pre-filled Pen (0.5ml Each) with caution in patients with ESRD.

Liver
SAFE IF PRESCRIBED

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Aplevant 1.5mg Pre-filled Pen (0.5ml Each) may not be needed in these patients. Please consult your doctor.

Frequently Asked Questions

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is to be taken only once a week at any time of the day with or without food. Consult your doctor for more advice.

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is injected under the skin (subcutaneously) of your stomach, thigh, or upper arm. It should not be injected into a muscle or vein. You can use the same area of your body each week to take the injection, but make sure that a different injection site is used within that area. Use Aplevant 1.5mg Pre-filled Pen (0.5ml Each) as advised by your doctor. You can take it with or without food. If you are on insulin as well, do not mix insulin and Aplevant 1.5mg Pre-filled Pen (0.5ml Each) in the same syringe. It is also recommended to check your blood sugar levels regularly.

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is used in type 2 diabetes mellitus. It improves blood sugar control and slows down digestion. This brings a feeling of fullness and satiety due to which the food intake by the patient decreases. As a result, the patient eats less which further helps in weight loss.

No, Aplevant 1.5mg Pre-filled Pen (0.5ml Each) is not an insulin. It is a medicine used to lower blood sugar (glucose) levels in adults with type 2 diabetes mellitus. In type 2 diabetes insulin is deficient, and the insulin that your body produces does not work as well as it should. Aplevant 1.5mg Pre-filled Pen (0.5ml Each) acts on the pancreas to increase insulin release, suppress glucagon secretion, and decrease glucose production from the liver. It also slows down the emptying of the stomach.

Yes, your doctor may prescribe you this medicine with insulin if adequate glucose management is not obtained after using Aplevant 1.5mg Pre-filled Pen (0.5ml Each) with other antidiabetic medicines. Insulin is often used early in the treatment of individuals with complications or symptoms of extremely high blood glucose levels. If insulin is used together with Aplevant 1.5mg Pre-filled Pen (0.5ml Each), there is often greater efficacy of both medications and improved treatment outcomes. <br>

No, Aplevant 1.5mg Pre-filled Pen (0.5ml Each) should not be used in patients with type 1 diabetes mellitus or for the treatment of patients with diabetic ketoacidosis.

There are reports of acute pancreatitis due to Aplevant 1.5mg Pre-filled Pen (0.5ml Each). Patients are prompted to discontinue this medicine and contact their doctor if there is persistent severe abdominal pain, sometimes radiating to the back.<br>

Regular self-monitoring of blood sugar is not needed in order to adjust the dose of Aplevant 1.5mg Pre-filled Pen (0.5ml Each). However, when initiating treatment with Aplevant 1.5mg Pre-filled Pen (0.5ml Each) in combination with other anti-diabetic medicines, monitoring of blood sugar may become necessary to reduce the dose of the anti-diabetic medicine in order to lower the risk of hypoglycemia. <br>

Avoid fried or fatty foods and foods high in sugar while taking Aplevant 1.5mg Pre-filled Pen (0.5ml Each) to reduce the risk of nausea and vomiting. Eat slowly, and eat smaller meals that are light and bland.

Aplevant 1.5mg Pre-filled Pen (0.5ml Each) should be refrigerated at 2°C - 8°C, but do not freeze it. Store Aplevant 1.5mg Pre-filled Pen (0.5ml Each) in the original packaging to protect from light. Keep the medicine out of the reach of children. Do not use the medicine if you notice that the pen is damaged or the medicine has become cloudy/discolored or has lumps in it.

Apart from the usual side effects of the medicine, Aplevant 1.5mg Pre-filled Pen (0.5ml Each) has been found to cause Medullary Thyroid Carcinoma, a type of cancer of the thyroid gland. Its use may also increase the risk of inflammation of the pancreas commonly known as pancreatitis which is a serious and painful condition. Discontinue the medicine and contact your doctor immediately if you suspect any signs or symptoms of thyroid problems (lump in throat, hoarseness, and difficulty in speaking) or pancreatitis (stomach ache radiating to the back, upper abdominal pain, fever, nausea, and vomiting).

Your doctor may ask you to get your HbA1c tested every 3 months. This test is done to see how well you have managed your blood sugar for the past 2-3 months.

Yes, Aplevant 1.5mg Pre-filled Pen (0.5ml Each) can be used alone or in combination with other diabetes medicines only if prescribed by your doctor.

Yes, you can take a diet rich in protein along with Aplevant 1.5mg Pre-filled Pen (0.5ml Each). Proteins are one of the major energy providers among all essential nutrients. Besides, being the building blocks of the human body, proteins break down into glucose to release energy. Unlike carbohydrates, the metabolism of proteins into glucose is much slower. Therefore, the release of energy usually takes a few hours after consumption. Thus, the spike in blood sugar levels might occur after a few hours when you are on a high-protein diet. It is often recommended to consume about 2-3 teaspoons of proteins in the evening snacks to avert the chances of hypoglycemia.<br><br>

No, artificial sweeteners are not good for people with diabetes. They are composed of chemicals that can cause mild to severe side effects. Thus, it is better to limit or avoid their use as much as you can.<br>

Yes, uncontrolled diabetes can cause kidney failure. In the long run, diabetes can affect the kidneys leading to a condition called diabetic nephropathy. Diabetic nephropathy is a condition that is a major cause of kidney failure in patients with diabetes. The best way to prevent damage to kidneys is by keeping diabetes in check, making dietary changes, monitoring sugar levels regularly, getting routine blood tests done, and taking prescribed medications on time.<br>

Diabetes is a condition that causes changes in your blood glucose levels, which if left uncontrolled, can lead to serious health complications affecting the heart, brain, kidneys, and eyes. However, with simple lifestyle changes, diet, and medications, one can manage their condition and lead a healthy life.

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