Mabtas 500mg Infusion
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Temperature-controlled dispatch across India within 4 to 24 hours.
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About this medicine
Mabtas 500mg Infusion (Rituximab (500mg))is a prescription oncology medicine. Below is educational product information — follow your doctor's advice for dose and use.
Mabtas 500 Infusion is used in the treatment of non-Hodgkin lymphoma (NHL), rheumatoid arthritis, blood cancer (chronic lymphocytic leukemia), granulomatosis with polyangiitis and microscopic polyangiitis.This medicine is given as an injection under the supervision of doctor. You must take it in a dose as advised by the doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.The most common side effects of this medicine include headache, weakness, edema, infection, and hair loss. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with hepatitis B.Before taking it, tell your doctor if you have heart disease, liver, or planning surgery or vaccination or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Quick Facts
Generic Name
Rituximab (500mg)
Dosage Form
Infusion
Prescription Status
Doctor's Rx Required
What if you miss a dose?
If you miss a dose of Mabtas 500 Infusion, please consult your doctor.\n
Uses of Mabtas 500mg Infusion
Side Effects of Mabtas 500mg Infusion
Oncology medicines should be administered strictly under medical supervision. Inform your oncologist immediately if you experience adverse symptoms.
Clinical Safety Advice for Mabtas 500mg Infusion
Follow expert clinical guidelines regarding interactions, precautions, and medical conditions when taking Mabtas 500mg Infusion.
Caution is advised when consuming alcohol with Mabtas 500 Infusion. Please consult your doctor.
Mabtas 500 Infusion may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Mabtas 500 Infusion is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
It is not known whether Mabtas 500 Infusion alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Mabtas 500 Infusion is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Mabtas 500 Infusion may not be needed in these patients. Please consult your doctor.
There is limited information available on the use of Mabtas 500 Infusion in patients with liver disease. Please consult your doctor.Use of Mabtas 500 Infusion is not recommended in patients with the active liver disease or those who had viral hepatitis as it can reactivate the infection.
Cold-Chain Temperature Protocol
Temperature-controlled cold-chain dispatch for Mabtas 500mg Infusion across India, with express delivery in Delhi NCR, Noida, and Ghaziabad.
Temperature Monitoring
Sourced from certified cold-storage warehouses.
Insulated Transit
Dispatched in gel-ice thermal insulated boxes.
Rx Verification
Prescription validated prior to cold dispatch.
Frequently Asked Questions
Clinical Overview: Mabtas 500mg Infusion
Mabtas 500 Infusion contains Rituximab, a highly effective monoclonal antibody. Manufactured by Intas Pharmaceuticals, it is a trusted biosimilar used primarily to treat specific types of blood cancers, such as Non-Hodgkin's Lymphoma (NHL) and Chronic Lymphocytic Leukemia (CLL), as well as severe autoimmune conditions like Rheumatoid Arthritis.
How It Works (Mechanism of Action)
Mabtas works by acting like a heat-seeking missile for your immune system. The Rituximab specifically seeks out and binds to a protein called 'CD20', which is found on the surface of certain white blood cells (B-cells). Once attached, it flags these abnormal or overactive B-cells so your body's natural immune defenses can recognize and destroy them, helping to clear the cancer or calm the autoimmune response.
Therapeutic & Treatment Context
In oncology, oncologists prescribe Mabtas either on its own or in combination with standard chemotherapy regimens (like CHOP) to treat B-cell lymphomas and leukemias. Outside of cancer, rheumatologists may prescribe it for patients with severe Rheumatoid Arthritis who have not responded well to other disease-modifying treatments.
Important Clinical Information & Precautions
Because Mabtas is a powerful biologic infusion, it must be administered by a healthcare professional in a clinic or hospital. Infusion-related reactions (like fever or chills) are common during the first dose, so your doctor will typically give you pre-medications (like paracetamol and an antihistamine) before starting the drip. It can also lower your immune system's ability to fight infections, so report any signs of fever or illness to your care team immediately.
Storage & Safe Handling Instructions
This biologic is highly sensitive to temperature changes. It must be strictly refrigerated between 2°C and 8°C (36°F to 46°F). It should never be frozen or shaken, and must remain in its original outer carton to protect it from light until it is prepared for your IV infusion.
Dosage & Administration Guidelines
Mabtas is given slowly through an intravenous (IV) drip. The exact dosage and schedule depend heavily on the condition being treated and your body surface area. The very first infusion is given very slowly over several hours so your medical team can monitor for any allergic reactions. If you tolerate the first dose well, future infusions can usually be given much faster.
Authoritative References & Medical Sources
- FDA Prescribing Information for RituximabUS FDAView Source
- NCCN Clinical Practice Guidelines in Oncology: B-Cell LymphomasNCCNView Source
Medical information standards
Educational product information for Mabtas 500mg Infusion. Not a substitute for advice from your treating doctor or healthcare provider.
- Reviewed by
- Nitin Kumar, D.Pharm (UPPC Reg: 63405)Lead Registered Pharmacist · 11 years clinical experience · Drug licence RLF21DL2025001406, RLF20DL2025001420. See our medical review policy.
- Content dates
- Catalogue copy is re-checked under our editorial standards. Pricing and stock update more often at checkout.
- Business address
- Vyloo Technologies Pvt. Ltd.
10251, F/F, Library Road, Nawab Ganj, Delhi G.P.O., Delhi, North Delhi- 110006, Delhi, IndiaGSTIN 07AAKCV0933E1ZF, 09AAKCV0933E1ZB. More on our drug licence page.
Authoritative references
- CDSCO (India) — Central Drugs Standard Control Organisation — Indian drug regulator
- Ministry of Health & Family Welfare — Government of India health ministry
- WHO Essential Medicines — World Health Organization essential medicines lists
- National Health Portal (India) — Government of India National Health Portal
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